Dynamic interaction graphs havebeenwidely adopted tomodeltheevolution of user-item interactions over time.

The dynamic nature of interactions between students and GenAI, as well as their relationship to writing quality, remains underexplored. While most research has examined how general-purpose GenAI can support writing, fewer studies have investigated how students interact with pedagogically designed systems across different phases of the writing process. To address this gap, we evaluated a GenAI-driven essay-writing assistant (EWA) designed to support higher education students in argumentative writing. Drawing on 1,282 interaction logs from 32 undergraduates during a two-hour writing session, Sequential Pattern Mining and K-Means clustering were used to identify behavioral patterns. Two clusters emerged: Cluster 1 emphasized outline planning and essay structure, while Cluster 2 focused on content development. A Mann-Whitney U test revealed a moderate effect size (r = 0.36) in the essay Organization dimension, with Cluster 1 showing higher scores. Qualitative analysis indicated that students with better performance actively wrote and shared essay sections with EWA for feedback, rather than interacted passively by asking questions. These findings suggest implications for teaching and system design. Teachers can encourage active engagement, while future EWAs may integrate automatic labeling and monitoring to prompt students to move from questioning to writing, enabling fuller benefits from GenAI-supported learning.

Understanding the movement behaviours of individuals and the way they react to the external world is a key component of any problem that involves the modelling of human dynamics at a physical level. In particular, it is crucial to capture the influence that the presence of an individual can have on the others. Important examples of applications include crowd simulation and emergency management, where the simulation of the mass of people passes through the simulation of the individuals, taking into consideration the others as part of the general context. While existing solutions basically start from some preconceived behavioural model, in this work we propose an approach that starts directly from the data, adopting a data mining perspective. Our method searches the mobility events in the data that might be possible evidences of mutual interactions between individuals, and on top of them looks for complex, persistent patterns and time evolving configurations of events. The study of these patterns can provide new insights on the mechanics of mobility interactions between individuals, which can potentially help in improving existing simulation models. We instantiate the general methodology on two real case studies, one on cars and one on pedestrians, and a full experimental evaluation is performed, both in terms of performances, parameter sensitivity and interpretation of sample results.

While transformers dominate modern vision and language models, their attention mechanism remains poorly suited for in-memory computing (IMC) devices due to intensive activation-to-activation multiplications and non-local memory access, leading to substantial latency and bandwidth overhead on ReRAM-based accelerators. To address this mismatch, we propose FAR, a Function-preserving Attention Replacement framework that substitutes all attention in pretrained DeiTs with sequential modules inherently compatible with IMC dataflows. Specifically, FAR replaces self-attention with a multi-head bidirectional LSTM architecture via block-wise distillation to retain functional equivalence while enabling linear-time computation and localized weight reuse. We further incorporate structured pruning on FAR models, enabling flexible adaptation to resource-constrained IMC arrays while maintaining functional fidelity. Evaluations on the DeiT family demonstrate that FAR maintains comparable accuracy to the original attention-based models on ImageNet and multiple downstream tasks with reduced parameters and latency. Further analysis shows that FAR preserves the semantic token relationships learned by attention while improving computational efficiency, highlighting its potential for energy-efficient transformer inference on IMC-based edge accelerators.

Efficiently leveraging simulation to acquire advanced manipulation skills is both challenging and highly significant. We introduce \textit{ForeRobo}, a generative robotic agent that utilizes generative simulations to autonomously acquire manipulation skills driven by envisioned goal states. Instead of directly learning low-level policies, we advocate integrating generative paradigms with classical control. Our approach equips a robotic agent with a self-guided \textit{propose-generate-learn-actuate} cycle. The agent first proposes the skills to be acquired and constructs the corresponding simulation environments; it then configures objects into appropriate arrangements to generate skill-consistent goal states (\textit{ForeGen}). Subsequently, the virtually infinite data produced by ForeGen are used to train the proposed state generation model (\textit{ForeFormer}), which establishes point-wise correspondences by predicting the 3D goal position of every point in the current state, based on the scene state and task instructions. Finally, classical control algorithms are employed to drive the robot in real-world environments to execute actions based on the envisioned goal states. Compared with end-to-end policy learning methods, ForeFormer offers superior interpretability and execution efficiency. We train and benchmark ForeFormer across a variety of rigid-body and articulated-object manipulation tasks, and observe an average improvement of 56.32\% over the state-of-the-art state generation models, demonstrating strong generality across different manipulation patterns. Moreover, in real-world evaluations involving more than 20 robotic tasks, ForeRobo achieves zero-shot sim-to-real transfer and exhibits remarkable generalization capabilities, attaining an average success rate of 79.28\%.

Designing protein binders targeting specific sites, which requires to generate realistic and functional interaction patterns, is a fundamental challenge in drug discovery. Current structure-based generative models are limited in generating nterfaces with sufficient rationality and interpretability. In this paper, we propose Retrieval-Augmented Diffusion for Aligned interface (RADiAnce), a new framework that leverages known interfaces to guide the design of novel binders. By unifying retrieval and generation in a shared contrastive latent space, our model efficiently identifies relevant interfaces for a given binding site and seamlessly integrates them through a conditional latent diffusion generator, enabling cross-domain interface transfer. Extensive exeriments show that RADiAnce significantly outperforms baseline models across multiple metrics, including binding affinity and recovery of geometries and interactions. Additional experimental results validate cross-domain generalization, demonstrating that retrieving interfaces from diverse domains, such as peptides, antibodies, and protein fragments, enhances the generation performance of binders for other domains. Our work establishes a new paradigm for protein binder design that successfully bridges retrieval-based knowledge and generative AI, opening new possibilities for drug discovery.

Cold-start drug-target interaction (DTI) prediction focuses on interaction between novel drugs and proteins. Previous methods typically learn transferable interaction patterns between structures of drug and proteins to tackle it. However, insight from proteomics suggest that protein have multi-level structures and they all influence the DTI. Existing works usually represent protein with only primary structures, limiting their ability to capture interactions involving higher-level structures. Inspired by this insight, we propose ColdDTI, a framework attending on protein multi-level structure for cold-start DTI prediction. We employ hierarchical attention mechanism to mine interaction between multi-level protein structures (from primary to quaternary) and drug structures at both local and global granularities. Then, we leverage mined interactions to fuse structure representations of different levels for final prediction. Our design captures biologically transferable priors, avoiding the risk of overfitting caused by excessive reliance on representation learning. Experiments on benchmark datasets demonstrate that ColdDTI consistently outperforms previous methods in cold-start settings.

Transforming road network data into vector representations using deep learning has proven effective for road network analysis. However, urban road networks' heterogeneous and hierarchical nature poses challenges for accurate representation learning. Graph neural networks, which aggregate features from neighboring nodes, often struggle due to their homogeneity assumption and focus on a single structural scale. To address these issues, this paper presents MSRFormer, a novel road network representation learning framework that integrates multi-scale spatial interactions by addressing their flow heterogeneity and long-distance dependencies. It uses spatial flow convolution to extract small-scale features from large trajectory datasets, and identifies scale-dependent spatial interaction regions to capture the spatial structure of road networks and flow heterogeneity. By employing a graph transformer, MSRFormer effectively captures complex spatial dependencies across multiple scales. The spatial interaction features are fused using residual connections, which are fed to a contrastive learning algorithm to derive the final road network representation. Validation on two real-world datasets demonstrates that MSRFormer outperforms baseline methods in two road network analysis tasks. The performance gains of MSRFormer suggest the traffic-related task benefits more from incorporating trajectory data, also resulting in greater improvements in complex road network structures with up to 16% improvements compared to the most competitive baseline method. This research provides a practical framework for developing task-agnostic road network representation models and highlights distinct association patterns of the interplay between scale effects and flow heterogeneity of spatial interactions.

What if the patterns hidden within dialogue reveal more about communication than the words themselves? We introduce Conversational DNA, a novel visual language that treats any dialogue -- whether between humans, between human and AI, or among groups -- as a living system with interpretable structure that can be visualized, compared, and understood. Unlike traditional conversation analysis that reduces rich interaction to statistical summaries, our approach reveals the temporal architecture of dialogue through biological metaphors. Linguistic complexity flows through strand thickness, emotional trajectories cascade through color gradients, conversational relevance forms through connecting elements, and topic coherence maintains structural integrity through helical patterns. Through exploratory analysis of therapeutic conversations and historically significant human-AI dialogues, we demonstrate how this visualization approach reveals interaction patterns that traditional methods miss. Our work contributes a new creative framework for understanding communication that bridges data visualization, human-computer interaction, and the fundamental question of what makes dialogue meaningful in an age where humans increasingly converse with artificial minds.